Genomics of Drug Sensitivity in Cancer
Compound: VE821
Drug Target: ATR
Drug Target pathway: Genome integrity
VE821 IC50 values for STAG2_mut
Screening concentration: 0.010005 (lower brown line) - 10.000 (upper brown line)
| STAG2_mut | Wild type | MWW p value | Signif | Selected | |
|---|---|---|---|---|---|
| Number of cell lines | 28 | 880 | |||
| Median | 15.599 | 55.045 | |||
| Geometric mean (red line) | 19.720 | 53.011 | |||
| Selected groups | 0.000317 | *** | |||
| ALL | 0 | 25 | - | - | |
| ACC | 0 | 1 | - | - | |
| BLCA | 1 | 17 | 0.77778 | - | |
| BRCA | 1 | 49 | 0.096292 | - | |
| CESC | 1 | 11 | 0.33333 | - | |
| CLL | 0 | 1 | - | - | |
| COREAD | 1 | 42 | 0.27666 | - | |
| DLBC | 0 | 32 | - | - | |
| ESCA | 0 | 34 | - | - | |
| GBM | 2 | 30 | 0.22756 | - | |
| HNSC | 0 | 39 | - | - | |
| KIRC | 0 | 30 | - | - | |
| LIHC | 0 | 15 | - | - | |
| LUAD | 0 | 61 | - | - | |
| LUSC | 0 | 14 | - | - | |
| LCML | 1 | 9 | 0.60000 | - | |
| LAML | 1 | 22 | 0.32712 | - | |
| LGG | 3 | 14 | 0.0029412 | ** | |
| MESO | 0 | 18 | - | - | |
| MB | 0 | 4 | - | - | |
| MM | 0 | 17 | - | - | |
| NB | 0 | 24 | - | - | |
| OV | 1 | 32 | 0.15625 | - | |
| PAAD | 0 | 29 | - | - | |
| PRAD | 1 | 4 | 0.40000 | - | |
| SKCM | 1 | 53 | 0.10871 | - | |
| STAD | 1 | 22 | 0.32712 | - | |
| SCLC | 0 | 57 | - | - | |
| THCA | 0 | 14 | - | - | |
| UCEC | 1 | 8 | 0.88889 | - | |
| UNCLASSIFIED | 12 | 152 | 0.011237 | * |
Select feature to draw Scatter plot
The Genomics of Drug Sensitivity in Cancer Project is a collaboration
between the Cancer Genome Project
at the Wellcome Sanger Institute (UK)
and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.
at the Wellcome Sanger Institute (UK)
and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.
https://www.cancerrxgene.org/compound/VE821/2111/scatter/STAG2_mut?tissue=PANCANCER&screening_set=GDSC2
Contact us | Cookies policy | Terms & Conditions.
This site is hosted by the Wellcome Sanger Institute.