Cell Line: PANC-10-05

Link to Cell Model Passport

DatasetDatasets
GDSC1: Screened in 96 or 384-well plates with Cyto60 or Resazurin endpoint
GDSC2 (recommended where available): 1536-well plates with CellTiterGlo endpoint
See documentation for more information and screening differences



Created with Raphaël 2.1.2Relative sensitivity of PANC-10-053.02.01.00.0-1.0-2.0Cell Line IC50 Z-ScoreDrugs (ranked by cell line sensitivity)resistantsensitive
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Drug
Targets
Z score
MG-132Proteasome, CAPN1-0.832581
POMHEX-0.71128
Bleomycin (50 uM)dsDNA break induction-0.633907
OSI-027MTORC1, MTORC2-0.572736
RefametinibMEK1, MEK2-0.520324
DasatinibABL, SRC, Ephrins, PDGFR, KIT-0.51981
123829-0.456026
UlixertinibERK1, ERK2-0.441568
PRIMA-1METTP53 activation-0.380933
UMI-77MCL1-0.346328
MethotrexateAntimetabolite-0.309973
PictilisibPI3K (class 1)-0.253464
SelumetinibMEK1, MEK2-0.253241
LinsitinibIGF1R-0.236792
PAK_5339PAK1, PAK2-0.199705
741909-0.184949
PD0325901MEK1, MEK2-0.154041
BleomycindsDNA break induction-0.148825
LapatinibEGFR, ERBB2-0.148381
XAV939TNKS1, TNKS2-0.130918
TrametinibMEK1, MEK2-0.101879
PevonedistatNAE-0.0977012
SCH772984ERK1, ERK2-0.0897295
DactolisibPI3K (class 1), MTORC1, MTORC2-0.0826884
LMP744TOP1-0.0733461
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